Nephrilin
Nephrilin (AC-EEED Peptide)
Kidney-protective peptide from diabetes research
Nephrilin is a small peptide that has shown kidney-protective effects in animal models of diabetic nephropathy. It reduces proteinuria and fibrosis in damaged kidneys.
Admin routes
Subcutaneous
Popularity
Niche
Side effects
Generally mild
AU vendors
0 rated
✓Key benefits
📈What to expect
No human data. Animal studies showed kidney protection over 4-8 weeks.
Based on community reports and published research. Individual results vary significantly.
💊Dosing protocols
Research reference
Varies by study
Daily in animal protocols
4-8 weeks in published studies
Dosing information is sourced from published research and community protocols. This is not a recommendation. Consult a healthcare professional.
Research status|Preclinical - animal models of diabetic nephropathy
Overview
Nephrilin was identified through research on diabetic kidney disease, where it demonstrated the ability to reduce proteinuria (protein in urine, a marker of kidney damage) and slow the progression of fibrosis in renal tissue. Diabetic nephropathy is the leading cause of kidney failure worldwide, and current treatments only slow progression rather than reversing damage. Nephrilin represents an attempt to directly protect and repair kidney tissue at the peptide level. Published data comes primarily from animal models of diabetic kidney injury.
⚙️How it works
Nephrilin appears to reduce TGF-beta signalling in renal tissue, suppressing the fibrotic cascade that leads to kidney scarring. It also reduces oxidative stress markers and inflammatory cytokine expression in the kidney. The exact receptor target has not been fully characterised.
⚡Side effects
📅Research history
Initial nephrilin studies in diabetic nephropathy models published
References
- [1]Kumar S, et al. 'Effect of Nephrilin peptide on diabetic kidney disease.' Peptides, 2014.
Frequently asked questions
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Disclaimer: This guide is for educational and informational purposes only. It is not medical advice. The dosing protocols listed are sourced from published research and community reports and do not constitute a recommendation. Always consult a qualified healthcare professional before using any peptide. Australian regulations classify many peptides as Schedule 4 (prescription-only) substances. Check current TGA guidelines before purchasing.