Pancragen
Pancragen (Lys-Glu-Asp-Trp)
Khavinson tetrapeptide for pancreatic function
Pancragen is a synthetic tetrapeptide bioregulator from the Khavinson group designed to support pancreatic function, particularly beta-cell health and insulin regulation.
Admin routes
Oral (capsule)
Popularity
Niche
Side effects
Generally mild
AU vendors
0 rated
✓Key benefits
📈What to expect
Possible improvement in blood glucose regulation (Russian reports)
Based on community reports and published research. Individual results vary significantly.
💊Dosing protocols
Metabolic support (Russian protocol)
10 mg (1-2 capsules)
1-2 times daily
10-20 day courses, 2-3 times per year
Dosing information is sourced from published research and community protocols. This is not a recommendation. Consult a healthcare professional.
Research status|Used in Russian clinical practice; limited Western peer review
Overview
Pancragen is a tetrapeptide (Lys-Glu-Asp-Trp) developed at the Saint Petersburg Institute of Bioregulation as a pancreatic tissue bioregulator. It is intended to normalise pancreatic function, particularly insulin production by beta cells. In Russian clinical data, it has been studied in patients with type 2 diabetes and metabolic syndrome. As with all Khavinson bioregulators, the evidence base is primarily Russian clinical studies, and the proposed mechanism of direct DNA interaction remains controversial in Western pharmacology.
⚙️How it works
According to Khavinson's theory, pancragen interacts with DNA regulatory regions in pancreatic beta cells, normalising gene expression related to insulin synthesis and secretion. It is proposed to restore age-declined beta-cell function rather than stimulating additional insulin release.
⚡Side effects
📅Research history
Pancragen developed at the Saint Petersburg Institute of Bioregulation
References
- [1]Khavinson VK. 'Peptide bioregulators: a new class of geroprotectors.' 2006.
Frequently asked questions
Related peptides
Community experiences
Share your experience with Pancragen. Effects, side effects, protocol details - help others make informed decisions.
No community reviews yet. Be the first to share your experience with Pancragen.
Need to calculate your dose?
Use our free reconstitution calculator to work out syringe units for Pancragen.
Open CalculatorFound this useful?
Share this guide
Disclaimer: This guide is for educational and informational purposes only. It is not medical advice. The dosing protocols listed are sourced from published research and community reports and do not constitute a recommendation. Always consult a qualified healthcare professional before using any peptide. Australian regulations classify many peptides as Schedule 4 (prescription-only) substances. Check current TGA guidelines before purchasing.